FORMULASI DAN EVALUASI SEDIAAN LOTION EKSTRAK KETUMBAR (Coriandrum sativum L.) SEBAGAI ANTI NYAMUK Aedes albopictus
نویسندگان
چکیده
Kasus Demam Berdarah Dengue (DBD) di Indonesia masih tergolong cukup tinggi, sehingga pengendalian vektor nyamuk penyebab DBD seperti Aedes albopictus sangat diperlukan. Penggunaan repellent (penolak nyamuk) yang berasal dari bahan alam dapat menjadi solusi untuk menurunkan kasus salah satunya menggunakan buah ketumbar (Coriandrum sativum L.). Buah memiliki kandungan senyawa metabolit sekunder menyebabkan kematian pada nyamuk. Penelitian ini bertujuan memformulasikannya dalam sediaan lotion kemudian dilakukan evaluasi diketahui konsentrasi baik. Jenis penelitian adalah eksperimental Laboratorium dengan membuat 4 formula terdiri F0 sebagai basis lotion, F1 ekstrak sebesar 60%, F2 65%, dan F3 70%. Pengujian selama 1 bulan terhadap stabilitas fisik ketumbar, pengujian tersebut meliputi organoleptik, homogenitas, pH, daya sebar, lekat, tipe emulsi. Berdasarkan hasil penelitian, formulasi menghasilkan baik setelah penyimpanan suhu ruang. Hasil menunjukkan bahwa 70% (formula 3) merupakan paling jika dibandingkan lainnya, hal karena memenuhi uji emulsi, tetapi sebar belum standar diperoleh syarat secara sempurna.
منابع مشابه
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ژورنال
عنوان ژورنال: Parapemikir: Jurnal Ilmiah Farmasi
سال: 2021
ISSN: ['2549-5062', '2089-5313']
DOI: https://doi.org/10.30591/pjif.v11i1.2767